Table 2.

Summary of methods used in studies on the adrenergic and noradrenergic innervation of the primate thalamus

Molecule studied	Authors	Genus	Fixation	Postfixation	Technique used	Plane of cutting	Stereotaxic space	Thalamic nomenclature	Parcellation stains	Studied thalamic regions
Adrenaline	Mefford et al. (1978)	Human	Unfixed	–	Liquid chromatography	Coronal	Not specified	Only major subdivisions	Fresh brain	Whole brain
PNMT	Rico and Cavada (1998a)	Macaque	Perfusion (PFA)	–	IMHQ	Coronal	YES	Olszewski (1952)	Nissl, AChE, Myelin	Whole thalamus
DßH	Vogt et al. (2008)	Macaque	Perfusion (PFA)	–	IMHQ	Coronal	Not specified	Olszewski (1952)	NeuN, Calbindin, Calretinin	Midline, mediodorsal, and intralaminar thalamic nuclei
NET	Smith et al. (2006)	Macaque	Unfixed	–	Autoradiography	Coronal	Not specified	Only major subdivisions	Not specified	Whole brain
DßH, NET and alpha adrenoceptors	Pérez-Santos et al. (2021)	Macaque	Perfusion (PFA) and unfixed	–	IMHQ and autoradiography	Coronal	YES (DßH and NET data)	Olszewski (1952)	Nissl, AChE, Myelin	Whole thalamus
Beta adrenoceptors	Reznikoff et al. (1986)	Human	Unfixed	–	Autoradiography	Coronal	Not specified	Only major subdivisions	Not specified	Whole brain

AChE Acetylcholinesterase, DßH dopamine-beta-hydroxylase, IMHQ immunohistochemistry, NET noradrenaline transporter, NeuN neuronal nuclear protein, PFA paraformaldehyde, PNMT phenylethanolamine N-methyltransferase