TABLE 1.

Detailed information on 15 SNPs of TRP channels and glutamatergic synapse genes.

No.	SNPs	Chr	Position	Gene	Region	A1	A2	MAF	HWE	References
1	rs11110359	12	100774548	SLC17A8	synon_exon2	G	A	0.138	0.101	Tag SNP
2	rs11568537	12	100813976	SLC17A8	—	A	C	0.180	0.083	Tag SNP
3	rs2229900	6	34008006	GRM4	synon_exon8	A	G	0.435	0.030	Tag SNP
4	rs2227283	6	102503317	GRIK2	synon_exon15	G	A/T	0.347	0.404	Tag SNP
5	rs3761555	X	122316437	GRIA3	upstream	T	C	0.349	0.000	Formicola et al. (2010) Maher et al. (2013) Fang et al. (2015)
6	rs3745521	19	51170706	SHANK1	nonsynon_exon22	A	G	0.456	0.270	Tag SNP
7	rs3020047	11	70935766	SHANK2	5′-UTR_exon1	T	C	0.127	1.000	Tag SNP
8	rs55678639	11	70316391	SHANK2	3′-UTR_exon23	A	G	0.203	0.138	Tag SNP
9	rs8065080	17	3480447	TRPV1	nonsynon_exon13	T	C	0.394	0.616	Yakubova et al. (2021)
10	rs222741	17	3508880	TRPV1	intron2	G	A	0.193	0.270	Carreño et al. (2012)
11	rs7217270	17	3421475	TRPV3	intron15	A	G	0.063	0.254	Carreño et al. (2012)
12	rs3742037	12	110226379	TRPV4	synon_exon13	G	A	0.181	0.492	Tag SNP
13	rs17862920	2	234827995	TRPM8	intron1	C	T	0.250	0.927	Gavva et al. (2019)
14	rs10166942	2	234825093	near TRPM8	upstream	T	C	0.355	0.549	Chen et al. (2018) Siokas et al. (2022)
15	rs7577262	2	234818869	TRPM8	upstream	G	A	0.373	0.941	Chasman et al. (2014) Fu et al. (2019)

Abbreviations: Chr, Chromosome; A1, major allele; A2, minor allele; MAF, minor allele frequency; HWE, hardy weinberg equilibrium.