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. 2023 May 26;10:1175483. doi: 10.3389/fmed.2023.1175483

Table 7.

Mediation effect of BMI on the association between serum and salivary biomarkers and average bedtime.

Biomarker Characteristics Estimate SE CI p-value
Serum CRP Direct effect 0.151 0.206 −0.253 0.554 0.464
Indirect effect 0.277 0.132 0.018 0.536 0.036
Total effect 0.428 0.245 −0.052 0.908 0.081
Serum IL-6 Direct effect 0.077 0.042 0.069 −0.006 0.160
Indirect effect 0.021 0.009 0.018 0.004 0.039
Total effect 0.098 0.042 0.018 0.017 0.180
Serum insulin Direct effect 0.017 0.020 0.404 −0.023 0.056
Indirect effect 0.022 0.011 0.047 0.0003 0.043
Total effect 0.038 0.023 0.095 −0.007 0.083

The confidence intervals and standard errors were obtained using 5,000 bootstraps. Goodness of fit tests: comparative fit index = 1.00, Tucker–Lewis index = 1.00. Size of residuals: standardized root mean squared residual = 0.00.