Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The mechanism of antioxidant system. System Xc-comprises SLC3A2 and SLC7A11 and promotes cellular uptake of cysteine, an essential precursor for GSH synthesis. GPX4 converts GSH to GSSG and returns PL-PUFA-OOH to the PL-PUFA-OH, achieving ferroptosis resistance.
