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. 2023 Jun 3;40:37–48. doi: 10.1016/j.jot.2023.05.002

Fig. 6.

Fig. 6

Effects of metformin on osteogenic differentiation of C3H10 ​cells induced by high glucose (A) Cell viability of C3H10 ​cells incubated with metformin for 24, 48, and 72 ​h (B) Effects of metformin on ALP activity in C3H10 ​cells induced by high glucose. Note: Vs. Control ∗P ​< ​0.05, ∗∗P ​< ​0.01, ∗∗∗P ​< ​0.001; vs. OIM #P ​< ​0.05, ##P ​< ​0.01, ###P ​< ​0.001; vs. OIM ​+ ​GH △P ​< ​0.05, △△P ​< ​0.01, △△△P ​< ​0.001. Values are presented as mean ​± ​SD.