Table 2.
Univariate and multivariate logistic regression results for the prediction of myocardial injury in hypertensive patients with COVID-19
| Characteristics | Univariate model | Multivariate model | |||
|---|---|---|---|---|---|
| OR | p-value | aOR | 95% CI | p-value | |
| Sex | |||||
| Male | 1 | 1 | |||
| Female | 0.66 | 0.268 | 1.43 | 0.25—8.21 | 0.689 |
| Age | < 0.001 | 0.129 | |||
| 28 to 49 years | 1 | 1 | |||
| 50 to 69 years | 3.09 | 0.053 | 0.84 | 0.08—8.36 | 0.881 |
| 70 to 97 years | 28.00 | < 0.001 | 5.71 | 0.48—67.3 | 0.166 |
| Oxygen Saturation | |||||
| > 93% | 1 | 1 | |||
| ≤ 93% | 3.63 | 0.001 | 3.41 | 0.53—21.7 | 0.194 |
| BMI (kg/m2) | 0.004 | 0.057 | |||
| ≤ 24,9 | 1 | 1 | |||
| 25 to 29.9 | 0.58 | 0.279 | 9.08 | 0.73—112.6 | 0.086 |
| ≥ 30 (obese) | 0.19 | 0.002 | 1.10 | 0.06—18.6 | 0.945 |
| Diabetes | |||||
| No | 1 | 1 | |||
| Yes | 2.82 | 0.003 | 6.04 | 0.97—37.7 | 0.054 |
| Cardiac comorbidities | |||||
| No | 1 | 1 | |||
| Yes | 5.20 | < 0.001 | 5.54 | 0.66—46.7 | 0.116 |
| Other comorbidities | |||||
| No | 1 | 1 | |||
| Yes | 8.41 | 0.001 | 4.68 | 0.26—82.9 | 0.292 |
| HLADR MFI > 1790 | |||||
| No | 1 | 1 | |||
| Yes | 47.30 | < 0.001 | 462.78 | 37.1—5.771 | < 0.001 |
| EGF < 196 | |||||
| No | 1 | 1 | |||
| Yes | 14.16 | < 0,001 | 3.56 | 0.57—22.3 | 0.175 |
| CD38 MFI < 4700 | |||||
| No | 1 | 1 | |||
| Yes | 6.69 | 0.001 | 35.14 | 2.66—464.5 | 0.007 |
| Total lymphocytes < 1740 | |||||
| No | 1 | 1 | |||
| Yes | 4.65 | 0.002 | 39.99 | 2.51—636.3 | 0.009 |
COVID-19, 2019 coronavirus disease; OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; BMI, body mass index; HLA-DR, human leukocyte antigen DR isotope; MFI, mean fluorescence intensity; EGF, epidermal growth factor