Table 2.
Network meta-analysis results for ranking of the treatments on all the outcome measures.
TSS reduction |
Nasal congestion score reduction |
Rhinorrhea score reduction |
Nasal itching score reduction |
Sneezing score reduction |
Ocular symptom score reduction |
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Treatment | SUCRA (%) | PrBest (%) | Mean rank | SUCRA (%) | PrBest (%) | Mean rank | SUCRA (%) | PrBest (%) | Mean rank | SUCRA (%) | PrBest (%) | Mean rank | SUCRA (%) | PrBest (%) | Mean rank | SUCRA (%) | PrBest (%) | Mean rank |
Rupatadine 10 mg | 76.3 | 0.6 | 3.4 | 73.4 | 0.8 | 3.7 | 74.6 | 2.9 | 3.5 | 47.1 | 0.4 | 6.3 | 66.5 | 0.4 | 4.4 | 88.8 | 12.8 | 2.1 |
Rupatadine 20 mg | 99.7 | 97.5 | 1.0 | 96.4 | 68.3 | 1.4 | 96.6 | 75.1 | 1.3 | 84.8 | 18.1 | 2.5 | 87.3 | 7.4 | 2.3 | 97.2 | 76.1 | 1.3 |
Ebastine 10 mg | 27.9 | 0.0 | 8.2 | 62.0 | 2.5 | 4.8 | 47.4 | 1.2 | 6.3 | 57.3 | 2.7 | 5.3 | 45.1 | 0.2 | 6.5 | 28.6 | 0.0 | 8.1 |
Ebastine 20 mg | 57.0 | 0.3 | 5.3 | 69.2 | 1.1 | 4.1 | 52.7 | 0.6 | 5.7 | 72.1 | 3.7 | 3.8 | 65.7 | 0.6 | 4.4 | 39.9 | 0.0 | 7.0 |
Fexofenadine 120 mg | 41.1 | 0.0 | 6.9 | 35.1 | 0.0 | 7.5 | 33.8 | 0.0 | 7.6 | 32.5 | 0.0 | 7.7 | 22.7 | 0.0 | 8.7 | 72.0 | 0.0 | 3.8 |
Fexofenadine 180 mg | 49.1 | 0.0 | 6.1 | 53.6 | 0.0 | 5.6 | 70.9 | 0.7 | 3.9 | 73.6 | 2.1 | 3.6 | 37.1 | 0.0 | 7.3 | 72.1 | 0.0 | 3.8 |
Levocetirizine 5 mg | 62.0 | 1.0 | 4.8 | 40.5 | 26.8 | 6.9 | 30.9 | 17.5 | 7.9 | 83.4 | 72.4 | 2.7 | 95.4 | 91.0 | 1.5 | 38.2 | 11.1 | 7.2 |
Cetirizine 10 mg | 63.5 | 0.2 | 4.6 | 35.1 | 0.0 | 7.5 | 71.0 | 0.8 | 3.9 | 32.4 | 0.0 | 7.8 | 59.4 | 0.0 | 5.1 | 48.9 | 0.0 | 6.1 |
Desloratadine 5 mg | 61.4 | 0.5 | 4.9 | 64.2 | 0.5 | 4.6 | 50.6 | 1.1 | 5.9 | 44.5 | 0.7 | 6.6 | 56.8 | 0.4 | 5.3 | 43.6 | 0.0 | 6.6 |
Loratadine 10 mg | 12.0 | 0.0 | 9.8 | 12.8 | 0.0 | 9.7 | 16.5 | 0.0 | 9.3 | 21.8 | 0.0 | 8.8 | 14.0 | 0.0 | 9.6 | 14.9 | 0.0 | 9.5 |
Placebo | 0.0 | 0.0 | 11.0 | 7.7 | 0.0 | 10.2 | 5.1 | 0.0 | 10.5 | 0.5 | 0.0 | 11.0 | 0.1 | 0.0 | 11.0 | 5.6 | 0.0 | 10.4 |
TSS, Total Symptom Score; SUCRA, Surface Under the Cumulative Ranking Curve; PrBest, Probability of Being the best.