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. 2023 May 15;15(5):3586–3596.

Table 2.

Comparison of blood lipid levels between groups before and after treatment

Variable Control group (n=55) PCSK9 inhibitor group (n=55) t P
TG (mmol/L) Before treatment 1.86±0.87 1.84±0.96 0.115 0.909
After treatment 1.52±0.73 1.21±0.81 2.108 0.037
t 2.220 3.719
P 0.029 <0.001
TC (mmol/L) Before treatment 5.78±1.15 5.81±1.35 -0.126 0.900
After treatment 4.61±1.04 3.67±1.03     4.7627 <0.001
t 5.596 9.346
P <0.001 <0.001
HDL-C (mmol/L) Before treatment 1.04±0.27 1.05±0.29 -0.187 0.852
After treatment 1.15±0.24 1.21±0.25 -1.284 0.202
t -2.258 -3.099
P 0.026 0.003
LDL-C (mmol/L) Before treatment 3.94±0.76 3.87±1.17 0.372 0.711
After treatment 2.51±0.86 1.82±0.97 3.947 <0.001
t 9.240 10.003
P <0.001 <0.001
Lp(a) (mg/L) Before treatment 321.23±102.43 320.78±100.96 0.023 0.982
After treatment 318.87±97.23 241.93±94.45 4.210 <0.001
t 0.124 4.230
P 0.902 <0.001

Note: All data are presented mean ± SD. Abbreviations: HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Lp(a), lipoprotein(a); PCSK9, proprotein convertase subtilisin/kexin 9; TC, total cholesterol; TG, triglycerides.