Table 3.
Comparison of inflammation levels between groups before and after treatment
| Variable | Control group (n=55) | PCSK9 inhibitor group (n=55) | t | P | |
|---|---|---|---|---|---|
| hs-CRP (mg/L) | Before treatment | 4.49±0.45 | 4.43±0.42 | 0.723 | 0.471 |
| After treatment | 3.53±0.34 | 3.01±0.26 | 9.010 | <0.001 | |
| t | 12.623 | 21.3194 | |||
| P | <0.001 | <0.001 | |||
| TNF-α (ng/L) | Before treatment | 124.56±23.45 | 126.87±22.46 | -0.528 | 0.599 |
| After treatment | 58.89±15.12 | 32.36±10.03 | 10.844 | <0.001 | |
| t | 17.455 | 28.4946 | |||
| P | <0.001 | <0.001 | |||
| IL-6 (pg/L) | Before treatment | 37.56±3.46 | 36.23±3.64 | 1.964 | 0.052 |
| After treatment | 20.39±2.09 | 17.72±1.45 | 7.784 | <0.001 | |
| t | 31.501 | 35.035 | |||
| P | <0.001 | <0.001 | |||
Note: All data are presented mean ± SD. Abbreviations: hs-CRP, high-sensitivity C-reactive protein; IL-6, interleukin 6; PCSK9, proprotein convertase subtilisin/kexin 9; TNF-α, tumor necrosis factor-alpha.