Table 3.
Correlations Between Baseline Complement Levels and Activities and Baseline GA Lesion Size in Treatment and Sham Groups (N = 81)
| Complement Levels/Activities | Correlation (rho) |
|---|---|
| Aqueous humor | |
| Bb | 0.141 |
| CFB | 0.142 |
| Bb:CFB | 0.099 |
| Intact C3 | 0.109 |
| Processed C3 | 0.109 |
| Processed:intact C3 | −0.047 |
| Intact C4 | 0.119 |
| Processed C4 | 0.119 |
| Processed:intact C4 | −0.105 |
| Plasma | |
| Bb | −0.196 |
| CFB | −0.217 |
| Bb:CFB | 0.060 |
| Intact C3 | −0.021 |
| Processed C3 | 0.007 |
| Processed:intact C3 | 0.008 |
| Intact C4 | −0.151 |
| Processed C4 | −0.052 |
| Processed:intact C4 | 0.047 |
C3 = complement component 3; C4 = complement component 4; CFB = complement factor B; GA = geographic atrophy.