Table 4.
Correlations Between Baseline Complement Levels and Activities and Annualized GA Lesion Growth Rate in the Sham Group Only (N = 26)
| Complement Levels and Activities | Correlation (rho) |
|---|---|
| Aqueous humor | |
| Bb | 0.147 |
| CFB | 0.126 |
| Bb:CFB | 0.081 |
| Intact C3 | 0.041 |
| Processed C3 | 0.066 |
| Processed:intact C3 | 0.256 |
| Intact C4 | −0.012 |
| Processed C4 | −0.010 |
| Processed:intact C4 | 0.222 |
| Plasma | |
| Bb | −0.193 |
| CFB | −0.244 |
| Bb:CFB | 0.056 |
| Intact C3 | −0.226 |
| Processed C3 | 0.148 |
| Processed:intact C3 | 0.256 |
| Intact C4 | −0.348 |
| Processed C4 | −0.029 |
| Processed:intact C4 | 0.209 |
C3 = complement component 3; C4 = complement component 4; CFB = complement factor B; GA = geographic atrophy.