Fig. 9. (a) A schematic illustration of subcutaneous surgical process, (b) weight loss % of the developed unloaded replacement G2 and G4, and the loaded replacement G2, G5 and G6 implants before and after animal sacrifice, and the photomicrographs of skin using collagen, CD8 and CD68 stain; control group G1 (c, i and o), unloaded 3D-printed ABS scaffold (d, j and p), 3D-printed ABS scaffold loaded RIF & LEV (e, k and q), unloaded 3D-printed PLA scaffold (f, l and r), 3D-printed PLA scaffold loaded-SIM (g, m and s), and the 3D-printed PLA scaffold loaded-SIM & PRP (h, n and t), respectively.