Table 11.
Relationship between antibiotic susceptibility using Vitek 2 system and gene expression level of recA and umuDC.
| Antibiotic | recA | umuDC | ||
|---|---|---|---|---|
| r | P | R | P | |
| TIC | 0.197 | 0.392 | 0.316 | 0.407 |
| TIC-CLV | 0.198 | 0.390 | 0.316 | 0.407 |
| PIP | 0.042 | 0.827 | 0.218 | 0.417 |
| PIP-TAZ | 0.035 | 0.856 | 0.198 | 0.461 |
| CAZ | 0.033 | 0.859 | 0.218 | 0.417 |
| CEF | 0.033 | 0.859 | 0.218 | 0.417 |
| CXN | 0.196 | 0.299 | 0.101 | 0.710 |
| CEX | 0.215 | 0.246 | 0.101 | 0.710 |
| ETN | 0.237 | 0.243 | 0.150 | 0.609 |
| IMP | -0.096 | 0.608 | -0.036 | 0.894 |
| MER | -0.026 | 0.910 | 0.561 | 0.073 |
| AK | -0.270 | 0.174 | 0.444 | 0.128 |
| GM | -0.280 | 0.142 | 0.198 | 0.461 |
| TOB | -0.141 | 0.542 | 0.168 | 0.643 |
| MNO | -0.321 | 0.366 | 0.000 | 1.000 |
| COL | -0.204 | 0.351 | 0.516 | 0.104 |
| TIG | -0.051 | 0.802 | 0.124 | 0.674 |
| CIP | -0.036 | 0.849 | 0.051 | 0.851 |
| LEV | -0.267 | 0.255 | -0.314 | 0.377 |
| TRI | 0.054 | 0.773 | 0.163 | 0.547 |
*
r – Spearman rank coefficient; p – p-value; TIC – Ticarcillin; TIC-CLV – ticarcillin-clavulanic acid; PIP – piperacillin; PIP-TAZ – piperacillin-tazobactam; CAZ – ceftazidime; CEF – cefepime; CXN – ceftriaxone; CEX – cefoxitin; ETN – Ertapenem; IMP – imipenem; MER – meropenem; MNO – minocycline; AK – Amikacin; GM – Gentamicin; TOB – Tobramycin; TIG – tigecycline; TRI – Trimethoprim-sulfamethoxazole; LEV – Levofloxacin; CIP – ciprofloxacin; COL – Colistin.