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. 2023 Jun 8;38(1):2220579. doi: 10.1080/14756366.2023.2220579

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 11. — Binding of compound 5f with EGFRT^790M, forming two HBs with Met793 and Lys745, nine HIs with Met766, Leu788, Ile759, Val726, Met790, Ala763, and Ala743, and three electrostatic attractions with Met790, Lys745, and Glu762.