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. 2023 Jun 8;38(1):2220579. doi: 10.1080/14756366.2023.2220579

Table 8.

Toxicity properties of the synthesised compounds.

Comp. MC-TD50a MTDRFb DTP RLD50b CLOAELb OI SI
5a 3.7461 0.129531 Non-toxic 0.483059 0.0375019 Irritant Non-irritant
5b 10.4772 0.138151 0.211542 0.0746137
5c 1.41938 0.0606517 0.450393 0.048643
5d 2.41863 0.137552 0.610853 0.0630163
6 29.8656 0.100448 0.359547 0.0709221 Irritant
7a 10.0095 0.221518 0.169431 0.12173 Non-irritant
5e 29.2894 0.108657 2.94856 0.323061
5f 10.6751 0.108657 2.61225 0.177435
7b 9.14814 0.133206 0.466603 0.129244
8 0.347134 0.0912244 0.705064 0.0718845
Erlotinib 8.05746 0.0827884 0.662169 0.0359487

aUnit: mg/kg/day.

bUnit: g/kg.