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. Author manuscript; available in PMC: 2023 Jun 9.
Published in final edited form as: J Am Coll Cardiol. 2023 Feb 21;81(7):623–632. doi: 10.1016/j.jacc.2022.11.051

TABLE 3.

Characteristics of Young Adults Stratified by Estimated 10-Year and 30-Year Cardiovascular Risk

Low 10-Year/Low 30-Year Risk (n = 403,679) Low 10-Year/Elevated 30-Year Risk (n = 6,425) Elevated 10-Year Riska (n = 4,156)

Age, y 29.6 ± 6.5 37.0 ± 2.2 32.7 ± 5.2
Sex
 Women 249,955 (61.9) 418 (6.5) 742 (17.9)
 Men 153,724 (38.1) 6,007 (93.5) 3,414 (82.1)
Race/ethnicity
 White 99,639 (24.7) 1,739 (27.1) 1,183 (28.5)
 Black 32,265 (8.0) 435 (6.8) 704 (16.9)
 Hispanic 186,621 (46.2) 2,950 (45.9) 1,476 (35.5)
 Asian/Pacific Islander 40,667 (10.1) 547 (8.5) 288 (6.9)
 Other 44,487 (11.0) 754 (11.7) 505 (12.2)
Systolic blood pressure, mm Hg 118.6 ± 14.1 137.1 ± 16.1 139.0 ± 18.1
Diastolic blood pressure, mm Hg 71.7 ± 10.2 83.6 ± 11.3 83.6 ± 12.3
Body mass index, kg/m2 28.5 ± 6.9 33.1 ± 6.8 34.2 ± 7.4
Total cholesterol, mg/dL 181.8 ± 34.8 223.5 ± 42.2 234.5 ± 57.6
HDL cholesterol, mg/dL 50.6 ± 13.0 39.4 ± 9.1 35.5 ± 8.5
LDL cholesterol, mg/dL 109.3 ± 30.0 137.4 ± 37.7 140.2 ± 43.0
 <100 160,477 (39.8) 980 (15.3) 668 (16.1)
 100–129 148,818 (36.9) 1,746 (27.2) 982 (23.6)
 130–159 71,390 (17.7) 2,054 (32.0) 1,242 (29.9)
 160–190 19,085 (4.7) 1,147 (17.9) 867 (20.9)
 ≥190 3,909 (1.0) 498 (7.8) 397 (9.6)
Current smoking 32,982 (8.2) 2,452 (38.2) 3,524 (84.8)
Treated hypertension 11,354 (2.8) 2,103 (32.7) 1,126 (27.1)
Diabetes 4,989 (1.2) 1,422 (22.1) 655 (15.8)
10-year risk, % 1.0 ± 1.0 4.5 ± 1.6 11.1 ± 5.9
 ≥7.5 0 (0.0) 0 (0.0) 4,156 (100.0)
 <7.5 403,679 (100.0) 6,425 (100.0) 0 (0.0)
30-year risk, % 4.3 ± 3.9 25.1 ± 5.2 26.9 ± 13.3
 ≥20 0 (0.0) 6,425 (100.0) 2,786 (67.0)
 <20 403,679 (100.0) 0 (0.0) 1,370 (33.0)
Lifetime risk, % 29.7 ± 14.9 52.5 ± 8.1 57.7 ± 10.7
 ≥39 162,636 (40.3) 6,373 (99.2) 4,139 (99.6)
 <39 241,043 (59.7) 52 (0.8) 17 (0.4)

Values are mean ± SD or n (%). Definitions for elevated and low cardiovascular risk: 10-year risk: elevated ≥7.5%, low <7.5%; 30-year risk: elevated ≥20%, low <20%. All P values <0.001 from analysis of variance (ANOVA) tests for continuous variables and chi-square tests for categoric variables across low 10-year/low 30-year risk vs low 10-year/ elevated 30-year risk vs elevated 10-year risk categories.

a

A total of 1,370 young adults had elevated 10-year but low 30-year risk, and they were included in the elevated 10-year risk group.

ASCVD = atherosclerotic cardiovascular disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein.