TABLE 3.
Low 10-Year/Low 30-Year Risk (n = 403,679) | Low 10-Year/Elevated 30-Year Risk (n = 6,425) | Elevated 10-Year Riska (n = 4,156) | |
---|---|---|---|
| |||
Age, y | 29.6 ± 6.5 | 37.0 ± 2.2 | 32.7 ± 5.2 |
Sex | |||
Women | 249,955 (61.9) | 418 (6.5) | 742 (17.9) |
Men | 153,724 (38.1) | 6,007 (93.5) | 3,414 (82.1) |
Race/ethnicity | |||
White | 99,639 (24.7) | 1,739 (27.1) | 1,183 (28.5) |
Black | 32,265 (8.0) | 435 (6.8) | 704 (16.9) |
Hispanic | 186,621 (46.2) | 2,950 (45.9) | 1,476 (35.5) |
Asian/Pacific Islander | 40,667 (10.1) | 547 (8.5) | 288 (6.9) |
Other | 44,487 (11.0) | 754 (11.7) | 505 (12.2) |
Systolic blood pressure, mm Hg | 118.6 ± 14.1 | 137.1 ± 16.1 | 139.0 ± 18.1 |
Diastolic blood pressure, mm Hg | 71.7 ± 10.2 | 83.6 ± 11.3 | 83.6 ± 12.3 |
Body mass index, kg/m2 | 28.5 ± 6.9 | 33.1 ± 6.8 | 34.2 ± 7.4 |
Total cholesterol, mg/dL | 181.8 ± 34.8 | 223.5 ± 42.2 | 234.5 ± 57.6 |
HDL cholesterol, mg/dL | 50.6 ± 13.0 | 39.4 ± 9.1 | 35.5 ± 8.5 |
LDL cholesterol, mg/dL | 109.3 ± 30.0 | 137.4 ± 37.7 | 140.2 ± 43.0 |
<100 | 160,477 (39.8) | 980 (15.3) | 668 (16.1) |
100–129 | 148,818 (36.9) | 1,746 (27.2) | 982 (23.6) |
130–159 | 71,390 (17.7) | 2,054 (32.0) | 1,242 (29.9) |
160–190 | 19,085 (4.7) | 1,147 (17.9) | 867 (20.9) |
≥190 | 3,909 (1.0) | 498 (7.8) | 397 (9.6) |
Current smoking | 32,982 (8.2) | 2,452 (38.2) | 3,524 (84.8) |
Treated hypertension | 11,354 (2.8) | 2,103 (32.7) | 1,126 (27.1) |
Diabetes | 4,989 (1.2) | 1,422 (22.1) | 655 (15.8) |
10-year risk, % | 1.0 ± 1.0 | 4.5 ± 1.6 | 11.1 ± 5.9 |
≥7.5 | 0 (0.0) | 0 (0.0) | 4,156 (100.0) |
<7.5 | 403,679 (100.0) | 6,425 (100.0) | 0 (0.0) |
30-year risk, % | 4.3 ± 3.9 | 25.1 ± 5.2 | 26.9 ± 13.3 |
≥20 | 0 (0.0) | 6,425 (100.0) | 2,786 (67.0) |
<20 | 403,679 (100.0) | 0 (0.0) | 1,370 (33.0) |
Lifetime risk, % | 29.7 ± 14.9 | 52.5 ± 8.1 | 57.7 ± 10.7 |
≥39 | 162,636 (40.3) | 6,373 (99.2) | 4,139 (99.6) |
<39 | 241,043 (59.7) | 52 (0.8) | 17 (0.4) |
Values are mean ± SD or n (%). Definitions for elevated and low cardiovascular risk: 10-year risk: elevated ≥7.5%, low <7.5%; 30-year risk: elevated ≥20%, low <20%. All P values <0.001 from analysis of variance (ANOVA) tests for continuous variables and chi-square tests for categoric variables across low 10-year/low 30-year risk vs low 10-year/ elevated 30-year risk vs elevated 10-year risk categories.
A total of 1,370 young adults had elevated 10-year but low 30-year risk, and they were included in the elevated 10-year risk group.
ASCVD = atherosclerotic cardiovascular disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein.