Figure 3.

Unrooted phylogenetic tree based on the aa sequence of the hypervariable region E of FCV strains detected in this study and cognate strains retrieved from the GenBank database. The tree was generated using maximum likelihood with the Jones–Taylor–Thornton (JTT) distance model, discrete gamma distribution, and a proportion of invariable sites, supplying statistical support with the bootstrapping of 1000 replicates. Black arrows indicate the FCV strains detected in this study. White arrows with black outlines indicate the limping strains retrieved from the GenBank databases. Abbreviations: LIM = limping pathotype; VAC = vaccine; ORD = oral respiratory disease; ENT = enteric pathotype; VSD = virulent systemic disease; CYS = cystitis pathotype; ABO = abortion pathotype; ASY = asymptomatic pathotype; UNK = unknown pathotype.