Table 4.
Effects of low pH, trypsin, and bile salts on infectivity of FCVs identified in this study.
| FCV Strain | Log10 Reduction of FCV Titer (log10 TCID50) Resulting from Control Virus and Treatment Indicated |
||
|---|---|---|---|
| HCL (pH 3.0) | Trypsin (0.5%) | Bile (0.5%) | |
| Δ | Δ | Δ | |
| 460.20-1 OS/ITA/2020 | 4.0 | 4.5 | 0.0 |
| 460.20-1-RS/ITA/2020 | 4.0 | 4.0 | 0.0 |
| 460.20-2 OS/ITA/2020 | 4.0 | 3.5 | 0.25 |
| 460.20-2 RS/ITA/2020 | 4.0 | 4.0 | 0.0 |
Note: Resistant phenotypes (null or modest decrease in the infectious titer) are indicated by grey shading. Abbreviations: OS, oropharyngeal swab; RS, rectal swab; Δ = log10 reduction.