Table 1.

Associations between cancer risk and temperament profile, cancer type, body type, and lifespan (p-values). Associations including osteosarcoma are shown at the top, while associations excluding osteosarcoma are show at the bottom. The “desirability group comparison” corresponds to the pairwise comparison of groups with less or more desirable temperament profiles. The more desired groups are calmer, and thus are less prone to stress, while the less desired groups are more prone to stress. In this table, n corresponds to the individual breed observations across studies. Significant effects are labeled with an asterisk (*).

Including Osteosarcoma		All Breeds in Studies Included n = 157, 69 Breeds				Singleton Breeds in Studies Removed n = 129, 41 Breeds
LCA Groups	Desirability Group Comparison	Temperament Effect	Cancer Type Effect	Body Size Effect	Lifespan Effect	Temperament Effect	Cancer Type Effect	Dog Size Effect	Lifespan Effect
2 groups	Best	0.7240	0.0387 *	3.3 × 10−5 *	0.1909	0.5032	0.1572	0.0006 *	0.4494
3 groups	Best	0.5881	0.0395 *	0.0001 *	0.1903	0.1230	0.1960	0.0074 *	0.5331
	Best and Mid	0.8579	0.0363 *	7.7 × 10−6 *	0.1992	0.7140	0.1154	0.0001 *	0.4885
4 groups	Best	0.6562	0.0390 *	0.0001 *	0.1938	0.2012	0.1788	0.0058 *	0.5537
	Best and 2nd Best	0.8427	0.0360 *	2.3 × 10−5 *	0.1918	0.9704	0.1282	0.0004 *	0.4828
	Best, 2nd Best, and 3rd Best	0.3482	0.0491 *	0.0001 *	0.2087	0.2213	0.2235	0.0015 *	0.5007
Not Including Osteosarcoma		All Breeds in Studies Included n = 85, 50 Breeds				Singleton Breeds in Studies Removed n = 73, 38 Breeds
LCA Groups	Desirability Group Comparison	Temperament Effect	Cancer Type Effect	Dog Size Effect	Lifespan Effect	Temperament Effect	Cancer Type Effect	Dog Size Effect	Lifespan Effect
2 groups	Best	0.6386	0.0515	0.3050	0.7681	0.8597	0.1147	0.4323	0.8069
3 groups	Best	0.8875	0.0484 *	0.2702	0.7956	0.9293	0.1032	0.3890	0.7798
	Best and Mid	0.4984	0.0644	0.3877	0.8198	0.9472	0.1176	0.4190	0.7858
4 groups	Best	0.8372	0.0432 *	0.1985	0.8222	0.6024	0.0865	0.2641	0.7478
	Best and 2nd Best	0.5484	0.0376	0.1212	0.7744	0.3289	0.0763	0.1652	0.8462
	Best, 2nd Best, and 3rd Best	0.4957	0.0637	0.3493	0.8118	0.9056	0.1232	0.4190	0.7861