Figure 6.

Schematic depiction of gliotic response involving macroglia in the late phase of diseased retinas in different species. Different colors of Müller cells and astrocytes underline the regenerative (blue) or degenerative (red) character of wound healing. In all models, macroglia have the ability to undergo the same gliotic response, but zebrafish do not show expression of all selected intermediate filaments and gliotic markers. This might be the reason for aberrant retinal tissue repair after retinal injury between both animal models. Created with BioRender.com.