AAVs	Adeno-associated viruses
ADP	Adenosine diphosphate
ALS	Amyotrophic Lateral Sclerosis
ALSFRS-R	Revised ALS Functional Rating Scale
AMPA	Aminomethylphosphonic acid
ASO	Antisense oligonucleotide
ATXN2	Ataxin-2
BMI	Body mass index
CBD	Cannabidiol
C9orf72	Chromosome 9 open reading frame 72
CNS	Central nervous system
CSF	Cerebrospinal fluid
DNMTs	DNA methyltransferases
dsRNAs	Double strand RNA
EAAT2	Excitatory amino acid transporter 2
EEG	Electroencephalographic
EMG	Electromyographic
ER	Endoplasmic reticulum
fALS	Familial ALS
FTD	Frontotemporal Dementia
FUS	Fused in sarcoma
FVC	Forced vital capacity
GABA	Gamma-aminobutyric acid
HDACi	Histone deacetylase inhibitors
iPSC	Induced pluripotent stem cells
miRNA	micro RNA
MME	motor-assisted movement exercisers
Nf	Neurofilaments
NfL	Neurofilament light chain
NGT	Nasogastric tube
NIV	Non-invasive ventilation
NMDA	N-methyl-D-aspartate
PAR	Poly Adenosine diphosphate (ADP)-ribose
PARP	Poly ADP-ribose polymerase
PEG	Percutaneous gastrostomy
PERK	Protein kinase Ribonucleic acid (RNA)-like endoplasmic reticulum kinase
PGRN	Progranulin
PTMs	Post-translational modifications
RIG	Radiologically inserted gastrostomy
RISC	RNA-induced silencing complex
RNA	Ribonucleic acid
sALS	Sporadic ALS
SCA2	Spinocerebellar Ataxia Type 2
siRNA	Small interfering RNA
SNP	Sniff nasal pressure
SOD1	Superoxide dismutase 1
TDP-43	Transactive response DNA binding protein 43 kDa
VC	Vital capacity