Table 6.
Cox simple regression.
| Predictor | N | Event N | HR (CI 95%) 1 | p-Value |
|---|---|---|---|---|
| Groups | ||||
| With irAEs | 34 | 12 | — | |
| Without irAEs | 45 | 20 | 2.13 (1.03 to 4.39) | 0.041 |
| Age | 79 | 32 | 0.99 (0.96 to 1.03) | 0.690 |
| Sex | ||||
| F | 25 | 6 | — | |
| M | 54 | 26 | 2.21 (0.91 to 5.38) | 0.080 |
| Smoking status |
||||
| Yes | 52 | 24 | — | |
| No | 23 | 6 | 0.47 (0.19 to 1.14) | 0.096 |
| Type of tumor | ||||
| ADK | 56 | 21 | — | |
| Squamous | 17 | 9 | 1.92 (0.87 to 4.27) | 0.108 |
| Other types | 6 | 2 | 0.79 (0.18 to 3.41) | 0.753 |
| ECOG performance status |
||||
| 0 | 21 | 4 | — | |
| 1 | 48 | 20 | 2.71 (0.92 to 7.97) | 0.070 |
| 2 | 10 | 8 | 9.55 (2.71 to 33.6) | <0.001 |
| Patients with chemotherapy | ||||
| Yes | 31 | 15 | — | |
| No | 48 | 17 | 0.90 (0.44 to 1.82) | 0.764 |
| Number of organs affected by metastasis |
53 | 32 | 1.60 (1.09 to 2.36) | 0.018 |
Legend: irAEs—immune-related adverse events; ADK—adenocarcinoma; HR—hazard ratio; CI—confidence interval; ECOG performance status—Eastern Cooperative Oncology Group performance status. 1 HR = Hazard Ratio, CI = Confidence Interval.