Tau 2N4R	Largest tau isoform in human CNS, 441 residues
[18F]CPFPX	(18)F-8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine
rolofylline	KW-3902, 1,3-dipropyl-8-(3-noradamantyl)xanthine, 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione
VOI	Volume of interest
TauΔK	Full-length tau (2N4R) with mutation ΔK280
TauRDΔK	Tau repeat domain (4R) with mutation ΔK280
AD	Alzheimer’s disease
FTLD	Frontotemporal lobar degeneration
CMRglu	Cerebral metabolic rate of glucose
CaMKIIα	Ca2+/Calmodulin-dependent protein kinase type II
PHF	Paired helical filament
GFAP	Glial fibrillary acidic protein
Iba 1	Ionized calcium-binding adapter molecule 1
DAB	3,3′-diaminobenzidine
NeuN	Neuronal nuclear protein
WT	Wild type
MB	Methylene blue
MWM	Morris water maze
NORT	Novel object recognition test
PET	Positron emission tomography
PSD-95	Post-synaptic density protein-95
CA1	Hippocampal area Cornu Ammonis 1
LCtrl	Littermate controls