Table 1. Major clinical characteristics of study subjects stratified by CAD severity.
| Variable | Controls (n = 55) | Mild CAD (n = 56) | Moderate CAD (n = 63) | Severe CAD (n = 55) | P-value |
|---|---|---|---|---|---|
| Age (years) | 59.40 ± 13.79 | 57.07 ± 8.67 | 60.32 ± 9.73 | 61.60 ± 8.64 | 0.132 |
| Male/female | 26/29 | 26/30 | 35/28 | 25/30 | 0.597 |
| BMI (kg/m2) | 24.60 ± 2.82 | 25.83 ± 3.22 | 27.63 ± 2.56 | 26.77 ± 4.03 | <0.001 |
| Smoking, n (%) | 8 (14.55%) | 8 (14.29%) | 15 (23.44) | 14 (25.45) | 0.248 |
| Hypertension, n (%) | 0 (0%) | 18 (32.14) | 27 (42.19%) | 31 (56.36) | <0.001 |
| Glucose (mmol/L) | 5.66 ± 1.13 | 5.67 ± 1.03 | 5.93 ± 1.78 | 6.84 ± 2.74 | <0.01 |
| CHO (mmol/L) | 4.35 ± 0.77 | 5.09 ± 0.83 | 5.16 ± 0.91 | 5.07 ± 1.18 | <0.001 |
| TG (mmol/L) | 1.54 ± 0.89 | 1.80 ± 0.92 | 1.86 ± 1.08 | 1.92 ± 1.02 | 0.188 |
| HDL-C (mmol/L) | 1.14 ± 0.28 | 1.19 ± 0.20 | 1.19 ± 0.24 | 1.19 ± 0.43 | 0.724 |
| LDL-C (mmol/L) | 2.52 ± 0.53 | 3.13 ± 0.71 | 3.20 ± 0.69 | 3.22 ± 1.03 | <0.001 |
Notes.
Patients were divided into control, mild, moderate and severe CAD based on the severity of coronary artery disease (CAD), continuous data are expressed as mean +/ − standard deviation and categorical variables are presented as numbers (percentages). Statistical significance at the P < 0.05 level. The one-way analysis of variance test including Bonferroni correction were used to perform group comparisons.
- CAD
- coronary artery disease
- BMI
- Body mass index
- HDL-C
- high-density lipoprotein cholesterol
- LDL-C
- low-density lipoprotein cholesterol
- CHO
- cholesterol; TG: Triglyceride