Table 3.
Histopathological Findings | Fibrotic HP (n = 12) |
Non-Fibrotic HP (n = 2) |
Non-HP (n = 4) |
---|---|---|---|
Fibrosis | 11 (92%) | 0 (0%) | 4 (100%) |
Chronic fibrosing IP | 11 | 0 | 4 |
Airway disease | 5 (42%) | 2 (100%) | 4 (100%) |
Airway-centered distribution | 4 | 2 | 3 |
Airway-centered fibrosis | 3 | 0 | 3 |
Peribronchiolar metaplasia | 5 | 0 | 4 |
Bronchiolitis | 4 | 2 | 1 |
Bridging fibrosis | 1 | 0 | 0 |
Poorly formed granuloma | 4 | 1 | 0 |
Inflammation | 11 (92%) | 2 (100%) | 4 (100%) |
Cellular IP | 10 | 2 | 4 |
Organizing pneumonia | 4 | 1 | 2 |
Cellular bronchiolitis | 2 | 1 | 1 |
Foamy macrophages | 3 | 2 | 0 |
Giant cells with cholesterol clefts | 2 | 0 | 0 |
Poorly formed granuloma | 4 | 1 | 0 |
Pathology pattern in GL [4] | |||
HP | 2 | 1 | 0 |
Probable HP | 2 | 0 | 3 |
Indeterminate for HP | 8 | 1 | 1 |
GL, guideline; HP, hypersensitivity pneumonitis; IP, interstitial pneumonia.