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. 2023 May 25;12(11):3663. doi: 10.3390/jcm12113663

Table 3.

Comparison of histopathological findings for each MDD diagnosis.

Histopathological Findings Fibrotic HP
(n = 12)
Non-Fibrotic HP
(n = 2)
Non-HP
(n = 4)
Fibrosis 11 (92%) 0 (0%) 4 (100%)
 Chronic fibrosing IP 11 0 4
Airway disease 5 (42%) 2 (100%) 4 (100%)
 Airway-centered distribution 4 2 3
 Airway-centered fibrosis 3 0 3
 Peribronchiolar metaplasia 5 0 4
 Bronchiolitis 4 2 1
 Bridging fibrosis 1 0 0
 Poorly formed granuloma 4 1 0
Inflammation 11 (92%) 2 (100%) 4 (100%)
 Cellular IP 10 2 4
 Organizing pneumonia 4 1 2
 Cellular bronchiolitis 2 1 1
 Foamy macrophages 3 2 0
 Giant cells with cholesterol clefts 2 0 0
 Poorly formed granuloma 4 1 0
Pathology pattern in GL [4]
 HP 2 1 0
 Probable HP 2 0 3
 Indeterminate for HP 8 1 1

GL, guideline; HP, hypersensitivity pneumonitis; IP, interstitial pneumonia.