Table 3.
Reusability test of the Cu(II)-CA catalyst in the CuAAC reaction a.
Run | Cu(II)-CA b |
---|---|
1 | 91 |
2 | 85 |
3 | 78 |
4 | 62 |
a Reaction conditions: azide (0.6 mmol), alkyne (0.5 mmol), H2O (3 mL), catalyst (5 mol% Cu), room temperature. b Isolated yield after 8 h.