Table 1.
Study patient characteristics.
| ILD Patients n = 114 |
Non-ILD Patients n = 6840 |
Total n = 6954 |
p-Value | |
|---|---|---|---|---|
| Age, years | 72.4 (13.6) | 62.9 (18) | 63.1 (18) | <0.001 |
| Male sex | 75 (65.8%) | 4009 (58.6%) | 83 (61.5%) | 0.148 |
| Current smoker | 6 (5.3) | 433 (6.3) | 439 (6.3) | 0.757 |
| Comorbidities | ||||
| Hypertension | 76 (66.7%) | 3287 (48.1) | 3363 (48.4) | <0.001 |
| Dyslipidemia | 58 (50.9%) | 2044 (29.9%) | 2102 (30.0%) | <0.001 |
| Diabetes | 39 (34.2%) | 1237 (18.1%) | 1276 (18.3%) | <0.001 |
| Cardiovascular disease | 50 (43.9%) | 1367 (20%) | 1417 (20.4%) | <0.001 |
| Obesity | 39 (34.2) | 1293 (18.9) | 1332 (19.2) | <0.001 |
| Chronic kidney disease | 23 (20.2) | 430 (6.3) | 453 (6.5) | <0.001 |
| Cerebrovascular disease | 16 (14.0) | 503 (7.4) | 519 (7.5) | 0.012 |
| Connective tissue disease | 13 (11.4) | 159 (2.3) | 172 (2.5) | <0.001 |
| Liver disease | 11 (9.6) | 247 (3.6) | 258 (3.7) | 0.002 |
| Home oxygen therapy | 20 (17.5) | 203 (3) | 223 (3.2) | <0.001 |
| Respiratory insufficiency on admission | 56 (49.1) | 2210 (32.3) | 2266 (32.6) | <0.001 |
| † Laboratory findings | ||||
| Lymphocytes, ×109/L | 1373.5 (2542.1) | 1401.8 (2616.2) | 1401.3 (2614.8) | 0.912 |
| Elevated LDH | 83 (72.8) | 4027 (58.9) | 4110 (59.1) | 0.004 |
| Elevated C-reactive proteins | 101 (88.6) | 5430 (79.4) | 5531 (79.5) | 0.024 |
| Elevated D-dimers | 74 (64.9) | 3583 (52.4) | 3657 (52.6) | 0.011 |
| Acute kidney failure during admission | 32 (28.1) | 984 (14.4) | 984 (14.4) | <0.001 |
| O2 used during admission | 88 (77.2) | 4636 (67.8) | 4724 (67.9) | 0.034 |
| Death during hospitalization | 36 (31.6%) | 1252 (18.3%) | 1288 (18.5%) | <0.001 |
| Death before follow-up | 42 (36.8%) | 1351 (19.8%) | 1393 (20.0%) | <0.001 |
Data are expressed as n (%) or mean (SD). ILD, interstitial lung disease; LDH, lactate dehydrogenase. † All laboratory findings are peak values except for lymphocytes, in which the lowest value is given.