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. 2023 May 26;12(11):3697. doi: 10.3390/jcm12113697

Table 1.

Characteristics of studies that reviewed outcomes in women with endometriosis after total or subtotal hysterectomy.

First Author/Year Sample Size (n) Type of Surgery Design Indication Main Results
Brunes, M., et al., 2021 [52] 1074 cases of endometriosis, 10,890 cases without endometriosis Total hysterectomy Nationwide cohort study Benign uterine disease The long-term prescription of analgesics was not reduced after hysterectomy in women with endometriosis.
Sandström, A., et al., 2020 [40] 137 Subtotal (n = 6) and total hysterectomy (n = 131) Population-based registry study Endometriosis Pelvic or lower abdominal pain was reduced by both methods.
Inés Poveda, G., et al., 2016 [53] 22 Total hysterectomy Retrospective study Deep endometriosis All of the variables, especially chronic pelvic pain, improved significantly after surgery.
Yunker, A., et al., 2015 [51] 35 (n = 8 cases of endometriosis) Subtotal hysterectomy Retrospective cohort study Endometriosis and benign indications Average nerve counts/high-power fields were 17.7 vs. 14.6 in patients with and without endometriosis, respectively.
Berner, E., et al., 2015 [32] 62 (n = 15 cases of endometriosis) Total (n = 7) and subtotal hysterectomy (n = 8) Randomized blinded controlled trial Dysmenorrhea Reduction of cyclic pelvic pain 12 months after hysterectomy did not differ between groups.
Berner et al., 2014 [44] 105 Subtotal hysterectomy (n = 14) Prospective observational study Endometriosis Cyclic pelvic pain was reduced to a minimum by 12 months and was associated with high patient satisfaction.
Brucker, Sara Y., et al., 2014 [42] 915 (n = 84 cases of endometriosis) Subtotal (n = 67) and total hysterectomy (n = 17) Prospective, questionnaire-based follow-up study Benign uterine disease There was no significant difference in the occurrence and persistence of postoperative pain.
Lieng, M., et al., 2010 [43] 449 (n = 64 cases of endometriosis) Subtotal hysterectomy Retrospective study Benign condition The mean pain score was significantly reduced.
Lieng, M., et al., 2008 [31] 240 Subtotal vs. total hysterectomy Retrospective study Benign conditions The data revealed a high level of patient satisfaction with subtotal hysterectomy.
Ghomi, A., et al., 2005 [39] 64 (n = 22 cases of endometriosis) Subtotal hysterectomy Prospective Benign conditions 23% of women with endometriosis reported cyclic bleeding at 15 months after surgery.
Fedele, L., et al., 2005 [54] 38 Total hysterectomy (n = 26) Descriptive study Symptomatic recurrences of deep endometriosis 31% of patients reported recurrent pain.
Ford, J., et al., 2004 [41] 60 Total hysterectomy (n = 9) Cohort study Rectovaginal endometriosis Patients achieved a considerably higher cure rate.
Okaro, E. O., et al., 2001 [29] 70 (n = 5 cases of endometriosis) Subtotal hysterectomy Retrospective study Menorrhagia and dysmenorrhea Symptoms related to the cervical stump were seen in all women with endometriosis.
Kim, K. S., et al., 2001 [55] 1 Total hysterectomy Case report Endometriosis Persistent endometriosis with vaginal and sigmoid–colonic invasion after total hysterectomy.
Nezhat, C. H., et al., 1996 [56] 6 Subtotal hysterectomy NA Persistent pelvic pain and endometriosis Five women had extensive pelvic endometriosis despite subtotal hysterectomy.
Namnoum, A., B. et al., 1995 [57] 138 Total hysterectomy Historical prospective study Endometriosis 21% of women had recurrent pain and needed repeat surgery.
Reich, H., et al., 1994 [58] 52 Total hysterectomy NA Endometriosis The majority of women achieved significant to complete relief from pelvic pain postoperatively.

Abbreviations: n: number; N/A: not available.