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. 2023 May 30;24(11):9486. doi: 10.3390/ijms24119486

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Bubbleplot of the Reactome pathways for glutamatergic, cholinergic and gabaergic synapses. The x-axis represents a score obtained by −log₂(FDR), so that pathways with score higher than 5 are significantly upregulated (red region in panel (A)) or downregulated (green region in panel (B)). Each point is filled with the color obtained with a score computed as −log₂(entities ratio).