Table 2.

Differentially expressed genes involved in gabaergic, cholinergic or dopaminergic synapsis.

Gene	CTRL	Δ8-THC	log2 Fold Change	q-Value	Synapsis
GABRA3	551.40	616.31	0.16	2.03 × 10−2	Gabaergic
GABRG3	50.57	98.84	0.97	1.12 × 10−6	Gabaergic
GABRR2	30.10	17.44	−0.79	2.27 × 10−2	Gabaergic
CHRNA3	3521.51	3364.80	−0.07	2.01 × 10−2	Cholinergic
CHRNA6	15.65	1.66	−3.24	1.60 × 10−4	Cholinergic
CHRNA7	2073.17	1844.79	−0.17	2.26 × 10−6	Cholinergic
CHRNB2	9219.72	8367.57	−0.14	5.31 × 10−18	Cholinergic
PRKACB	3247.01	3042.53	−0.09	1.17 × 10−3	Cholinergic
MAPK1	1856.47	1716.04	−0.11	3.28 × 10−3	Cholinergic
CREB3L3	13.24	4.98	−1.41	1.67 × 10−2	Cholinergic
CREB3L4	1438.70	1281.63	−0.17	1.24 × 10−4	Cholinergic
CREB5	2677.55	2544.16	−0.07	2.34 × 10−2	Cholinergic
SLC18A3	280.52	213.47	−0.39	1.11 × 10−4	Cholinergic
DRD4	108.35	54.82	−0.98	3.20 × 10−8	Dopaminergic
CALY	7.22	1.66	−2.12	2.62 × 10−2	Dopaminergic
DDC	13,066.29	12,497.37	−0.06	4.46 × 10−6	Dopaminergic

For each DEG, the difference in the level of expression computed by log₂(∆⁸-THC/CTRL) results in the log₂ fold change. The post hoc correction of the p-value is highlighted in q-Value column. All values were rounded to the second decimal digit.