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. 2023 May 31;24(11):9533. doi: 10.3390/ijms24119533

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Fecal bacteria composition in Enterotype Bacteroidaceae (ET-B). In US adults with ET-B, the T2DM group exhibited a higher proportion of Bacteroides, Facalibacterium, Lachnoclostridium, and Blautia, while the proportion of Allistipes was lower in abundance than the healthy group. The interactions among bacterial families and genera were more robust in the T2DM group than in the healthy group. (A). Relative abundance of fecal bacteria compositions at the genus level between type 2 diabetes (T2DM) and healthy groups. (B). Primary bacteria between the type 2 diabetes (T2DM) and healthy groups at the species level by XGboost in each enterotype. (C). Network of primary bacteria in the T2DM and healthy groups according to each enterotype. Red and blue lines indicate positive and negative correlations with Pearson correlation coefficient > 0.1, respectively (p < 0.001). * Significant differences between T2DM and healthy groups at p < 0.00001 (Bonferroni corrected p value).

Fecal bacteria composition in Enterotype Bacteroidaceae (ET-B). In US adults with ET-B, the T2DM group exhibited a higher proportion of Bacteroides, Facalibacterium, Lachnoclostridium, and Blautia, while the proportion of Allistipes was lower in abundance than the healthy group. The interactions among bacterial families and genera were more robust in the T2DM group than in the healthy group. (A). Relative abundance of fecal bacteria compositions at the genus level between type 2 diabetes (T2DM) and healthy groups. (B). Primary bacteria between the type 2 diabetes (T2DM) and healthy groups at the species level by XGboost in each enterotype. (C). Network of primary bacteria in the T2DM and healthy groups according to each enterotype. Red and blue lines indicate positive and negative correlations with Pearson correlation coefficient > 0.1, respectively (p < 0.001). * Significant differences between T2DM and healthy groups at p < 0.00001 (Bonferroni corrected p value).