Table 4.
The first result of detected pathogen in SD and ISEE treated with EAT or TAT.
| Procedure of First Pathogen Detection | TAT | EAT | ||||
|---|---|---|---|---|---|---|
| SD | ISEE | p-Value * | SD | ISEE | p-Value * | |
| Blood culture | 31/53 (58.5%) | 6/15 (40%) | 0.340 | 50/89 (64.9%) | 18/51 (38.3%) | 0.008 |
| Intraoperative specimens | 21/53 (39.6%) | 8/1 (53.3%) | 24/89 (31.2%) | 28/51 (59.6%) | ||
| CT-guided Biopsy | 1/53 (1.9%) | 1/15 (6.7%) | 3/89 (3.9%) | 1/51 (2.1%) | ||
| Unknown pathogens | 0 | 0 | 12 | 4 | ||
ISEE: isolated spinal epidural empyema, SD: spondylodiscitis, CT: computer tomography, EAT: empiric antibiotic therapy, TAT: targeted antibiotic therapy, *: Fisher exact test. Bold values are significant results (p < 0.05) as indicated in the methods.