Inhibitory effects of compounds 4a–o against MAO-A, MAO-B, AChE and BChE.

Compound	MAO-A	MAO-B	AChE	BChE
	aIC50 ± SEMb (μM)/% age inhibition
4a	33.23c	37.06c	42.32%c	20.54%c
4b	2.86 ± 1.51b	35.73c	31.34%c	23.65%c
4c	1.90 ± 0.25b	0.80 ± 0.27c	36.12%c	14.76%c
4d	1.44 ± 0.22b	1.04 ± 0.22c	0.83 ± 0.007a	23.67%c
4e	1.47 ± 0.45b	1.91 ± 0.89	1.96 ± 0.176a	10.54%c
4f	34.82c	39.46c	2.03 ± 0.434a	22.61%c
4g	1.21 ± 0.04b	2.02 ± 1.26	1.11 ± 0.080a	15.23%c
4h	21.87c	29.36c	1.51 ± 0.462a	12.43%c
4i	38.11c	32.53c	37.12%c	21.45%c
4j	1.02 ± 0.09b	18.57c	1.56 ± 0.309a	20.55%c
4k	3.46 ± 2.58b	1.10 ± 1.16	39.65%c	14.67%c
4l	36.81c	24.86c	44.56%c	26.91%c
4m	0.11 ± 0.001b	3.08 ± 0.06c	2.67 ± 0.029a	15.78%c
4n	21.07c	18.47c	1.23 ± 0.969a	28.87%c
4o	29.98c	22.65c	2.32 ± 0.080a	32.98%c
Clorgylined	0.005 ± 0.03	61.35 ± 1.13	—	—
Deprenyld	67.25 ± 1.02	0.019 ± 0.01	—	—
Donepezild	—	—	0.032 ± 0.003a	6.41 ± 0.34a

^aIC₅₀ half-maximal half inhibitory concentration in micromolar range.

^bSEM standard error mean.

^c%age inhibition.

^dPositive control.