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. 2023 Jun 1;12(11):3815. doi: 10.3390/jcm12113815

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Mean values of serum creatinine (mg/dL) in all experimental groups. Diabetes induction increased this value (p < 0.001), but empagliflozin therapy reduced it (p < 0.001) at days 36th (* (p < 0.001)) showing a significant difference when compared with the control (C) group; # (p < 0.001) and a significant difference when compared with the diabetic (D) group (1 = day 0 or first examination, 2 = day 36). (C = control, CE = control plus empagliflozin, D = diabetes, DE = diabetes plus empagliflozin).