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. 2023 May 29;24(11):9453. doi: 10.3390/ijms24119453

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Examination of STAT3, cyclinD1, and Bcl-2 mRNA levels in A172 and LN428 cells after Res, TMZ, or Res + TMZ treatments for 48 h using qRT-PCR (A) and ICC (B). GAPDH was used as an internal control. All of the results represent the mean ± standard deviation of three independent experiments (n = 3). *, p < 0.05, compared with the Ctrl group; #, p < 0.05, compared with the R50 or T500. Ctrl, control group; R50, resveratrol 50 μM; T500, temozolomide 500 μM; R50T500, combined treatment of resveratrol 50 μM and temozolomide 500 μM. Scale bar = 50 μm.