Figure 1.

Principles of membrane oxygenation during hypothermic kidney machine perfusion. Between the pump and the organ chamber, a membrane oxygenator is added in series. In the membrane oxygenator, oxygen diffuses from the gas compartment through the thin gas-permeable membrane into the perfusion fluid, and carbon dioxide diffuses from the perfusion fluid into the gas compartment for disposal. By arterial cannulation, the oxygenated perfusion fluid is pumped through the kidney. The reservoir of the organ chamber collects the perfusion fluid via open venous drainage and is pumped again towards the membrane oxygenator. Figure and figure legend slightly adapted but based on Figure 1 of T. Darius et al. [16].