Figure 1.

Echocardiographic primary endpoints at baseline and 8 weeks after randomization to diuretics (chlorthalidone + amiloride; dark boxes) or amlodipine (light boxes). (a) Left ventricular global longitudinal strain; (b) Right ventricular global longitudinal strain. (c) Tissue Doppler early septal mitral annulus displacement peak velocity (d) Ratio of the early mitral inflow peak velocity to the tissue Doppler early septal mitral annulus displacement peak velocity; p for comparison between baseline and 8 weeks measurements, the remaining comparisons were not statistically significant.