Table 1.

Effects of multipotent mesenchymal stromal cells at “thin” endometrium and Asherman’s syndrome.

Authors	Type of MMSC	Model	Results	References
Kilic, S. et al.	MMSCs from the bone marrow and umbilical cord	Rat model of AS	Increased endometrial vascularization and decreased fibrosis	[74]
Pekarev, O.G. et al.	Human umbilical cord MSC	Rat model of a uterine scar	Stimulating effect on vascular remodeling and the formation of de novo formed vessels in the uterine scar	[75]
Zhu, H. et al.	Menstrual stem cells	In vitro	Increased proliferation of endometrial stromal cells, suppression of myofibroblast differentiation	[77]
Zhao, J. et al.	Autologous bone marrow derived MSC	Rat model of “thin” endometrium	Increased the ET, activated the expression of markers of regeneration and receptivity, anti-inflammatory effects	[78]
Tan, J. et al.	Autologous menstrual blood-derived stromal cells	Patient’s with severe AS	Increased the ET (71%), pregnancy (71%), live birth (29%)	[81]
Zhao, Y. et al.	Autologous bone marrow derived MSC	Patient’s with intrauterine adhesions	Restoration of the endometrium in a woman with refractory AS	[80]
Cao, Y. et al.	Umbilical cord MSCs on collagen scaffolds	Patients with Recurrent Uterine Adhesions	Increased in the ET (100%), pregnancy (38%)	[84]
Zhang, Y. et al.	Umbilical cord MSC on collagen scaffolds	Patients with AS	Increase in ET (100%), pregnancy (31%), live birth (12%)	[85]