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. 2023 May 26;24(11):9328. doi: 10.3390/ijms24119328

Table 4.

Advantages and disadvantages of metformin.

Daily Dosage Advantages Side Effects Contraindications

  • 500–2550 mg (depending on immediate vs. extended-release formulations)

  • Weight loss

  • Inexpensive

  • Diarrhea

  • Vomiting

  • Dyspepsia

  • Flatulence

  • Metallic taste

  • Lactic acidosis

  • Renal disease

  • Heart failure

  • Liver disease

  • Hypoxic pulmonary disease