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. 2023 May 26;24(11):9328. doi: 10.3390/ijms24119328

Table 9.

Advantages and disadvantages of Dipeptidyl peptidase-4 (DPP-4) inhibitors.

Daily Dosage Advantages Side Effects Contraindications
  • Sitagliptin (50–100 mg)

  • Saxagliptin (2.5–5 mg)

  • Vildagliptin (50–100 mg)

  • Linagliptin (5 mg)

  • Weight loss

  • Hypoglycemia

  • Pancreatitis

  • GI distress

  • Flu-like symptoms

  • Joint pain

  • Pregnancy

  • Pancreatitis

  • Heart failure

  • Angioedema