Table 4.
Altered metabolic pathways (raw p < 0. 05, FDR < 0.15) and altered metabolites in different pathways.
| Pathway | Raw p | FDR | Total Metabolites in the Pathway |
Hits Metabolites | Altered Metabolites | Type |
|---|---|---|---|---|---|---|
| Butanoate metabolism |
0.0004 | 0.02 | 15 | 4-Aminobutanoate L-Glutamate |
L-Glutamate | Down |
| Histidine metabolism |
0.0070 | 0.13 | 16 | L-Glutamate L-Histidine N(pi)-Methyl-L-histidine L-Aspartate |
L-Glutamate L-Aspartate |
Down Down |
| Alanine aspartate and glutamate metabolism |
0.0135 | 0.13 | 28 | L-Aspartate L-Asparagine L-Alanine L-Glutamate 4-Aminobutanoate L-Glutamine |
4-Aminobutanoate L-Glutamate | Down Down |
| Arginine and proline metabolism |
0.0161 | 0.13 | 38 | L-Arginine 4-Aminobutanoate Putrescine Hydroxyproline L-Proline L-Glutamate L-Ornithine |
4-Aminobutanoate L-Glutamate | Down Down |
| Nicotinate and nicotinamide metabolism |
0.0164 | 0.13 | 15 | L-Aspartate | L-Aspartate | Down |
| Porphyrin and chlorophyll metabolism |
0.0173 | 0.13 | 30 | Glycine L-Glutamate |
L-Glutamate | Down |
| D-Glutamine and D-glutamate metabolism |
0.0253 | 0.14 | 6 | L-Glutamate L-Glutamine |
L-Glutamate | Down |
| Nitrogen metabolism |
0.0253 | 0.14 | 6 | L-Glutamate L-Glutamine |
L-Glutamate | Down |