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The effect of 48 h of incubation with irinotecan (5 μM and 20 μM), melatonin (2000 µM), wogonin (25 μM), celastrol (0.625 μM and 1.25 μM), and their combinations on the spheroid growth of LOVO cells. Abbreviations: Iry (irinotecan), Mel (melatonin), Cel (celastrol), Wog (wogonin).
