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. 2023 May 31;24(11):9536. doi: 10.3390/ijms24119536

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Perfusate cytokine levels at 1 h NMP and at the end of NMP of transplanted DBD and DCD livers. Anti-inflammatory cytokines (A) IL-4, (B) IL-12 p70, (C) IL-13, and pro-inflammatory cytokines (D) GM-CSF, (E)TNFα, (F) IFNγ, (G) IL-1β, (H) IL-2, (I) IL-5, (J) IL-6 and (K) IL-18 are shown as individual values and medians for DBD (solid circles) and DCD (open boxes) livers. (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001; ANOVA tests between time points and between the groups; details are described in the section on statistical analysis). NMP, normothermic machine perfusion. h, hour; IL, Interleukin; GM-CSF, granulozyte-monozyte colony-stimulating factor; TNFα, tumor necrosis factor alpha; IFNγ, interferon gamma.