Figure 11.

Analysis of succinate-linked mitochondrial respiration in tissue biopsies of declined DBD and DCD livers pre-NMP, at 1 h NMP and at the end of NMP. (A) OXPHOS capacity, (B) P-L control efficiency, (C) LEAK respiration and (D) cytochrome c control efficiency were measured and calculated following the protocol as described in Table S2. Values are represented as single data points, medians and interquartile ranges for DBD (solid circles) and DCD (open boxes) livers. NMP, normothermic machine perfusion; h, hour; DBD, donation after brain death; DCD, donation after circulatory death.