Table 16.
Kinase spectrum of 122d against RTK.
| Compd. | IC50 (nM) | |||||||
|---|---|---|---|---|---|---|---|---|
| PDGFRα | VEGFR2 | FGFR1 | c-KIT | PDGFRβ | FLT3 | VEGFR1 | VEGFR3 | |
| 122d | 40 | 1225 | >50,000 | 2.1 | 197 | 1880 | 3493 | 376 |
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