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The pathogenesis of DM2 in terms of inflammation. Abbreviations: DM2, type 2 diabetes mellitus; hs-CRP, high-sensitivity C-reactive protein; ICAM-1, intercellular adhesion molecule-1; IL, interleukin; IR, insulin resistance; NLPR3i, domain-like receptor protein 3 (NLRP3) inflammasome; TNF-α, tumor necrosis factor α; VCAM-1, vascular cell adhesion molecule-1.
