Table 1.
Physicochemical properties of new nitroimidazole sulfonamide radiosensitiser compounds.
| No. | Structure | Purity % | Solubility 1 (mM) | % Stability in αMEM |
|---|---|---|---|---|
| 13 |
|
99.6 | 110 | 99.3 |
| 14 |
|
98.9 | 95.8 | 98.5 |
| 15 |
|
99.3 | 84.3 | 99.9 |
| 16 |
|
99.8 | 83.05 | 99.9 |
| 17 |
|
98.4 | >101.2 | 100.0 |
1 Solubility in α-MEM culture medium containing 5% foetal calf serum.