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. 2023 Jun 7;11(6):e006802. doi: 10.1136/jitc-2023-006802

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Comparison of the peripheral immune signature in M-MDSC-high versus M-MDSC-low patients. Violin plots depicting blood counts from the hemogram (A) and flow cytometry-derived frequencies of myeloid cells, T cells and their checkpoint receptor expression (B). *P<0.05, **p<0.01, ***p<0.005, ****p<0.0001. LAG-3, lymphocyte activation gene 3; M-MDSC, monocytic myeloid-derived suppressor cell; NLR, neutrophil-to-lymphocyte ratio; PD-1, programmed cell death protein 1; TIM-3, T cell immunoglobulin and mucin-domain containing-3; Treg, regulatory T cell.