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Comparison of significant changes in the abundance of immune cell subsets under immune checkpoint blockade in M-MDSC-high versus M-MDSC-low patients: eosinophils (A), checkpoint receptor expression on T cells (B) and total CD4+ T cell frequencies (C). *P<0.05, **p<0.01, ***p<0.005, ****p<0.0001. BL, baseline; FU, follow-up; LAG-3, lymphocyte activation gene 3; M-MDSC, monocytic myeloid-derived suppressor cell; TIM-3, T cell immunoglobulin and mucin-domain containing-3.
