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. 2023 Jun 7;11(6):e006802. doi: 10.1136/jitc-2023-006802

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Comparison of changes in the M-MDSC frequencies in M-MDSC-low versus M-MDSC-high patients under immune checkpoint blockade. Patients in the M-MDSC-high group had a significant decrease in their M-MDSC frequencies (A, p=0.010). Those patients whose M-MDSC frequency stayed high had a significantly shorter overall survival compared with those with a decrease or an M-MDSC frequency that stayed low (B). **P<0.01. BL, baseline; FU, follow-up; M-MDSC, monocytic myeloid-derived suppressor cell; PBMC, peripheral blood mononuclear cell.